Autophagy, which declines with age, may hold more mysteries than researchers previously suspected. Scientists have now uncovered possible novel functions for various autophagy genes, which may control ...

Researchers reveal how a nanomachine takes care of cleaning up inside the cell. To prevent our body's cells from overflowing with garbage and to keep them healthy, the waste inside them is constantly ...

Autophagy is a self-eating process for recycling and rejuvenating cellular organelles and components. Intracellular calcium dynamics has been shown to be essential for the initiation of the autophagy ...

The mechanism of astrocytic autophagy plasticity plays a crucial role in AD. When the autophagy-regulating genes (LC3B and SQSTM1) in astrocytes are activated, Aβ is efficiently removed, which is ...

Research from investigators at Rutgers Cancer Institute of New Jersey and the Herbert Irving Comprehensive Cancer Center at Columbia University Medical Center, shows the intracellular process of ...

Autophagy has been shown to be a key player in preventing aging and diseases of aging, including cancer, cardiovascular disease, diabetes, and neurodegeneration. Notably, research has shown that ...

Our immune system has various ways to deal with threats from the outside like pathogens. One of the defence mechanisms is a process called autophagy. 'You can imagine autophagy as the vacuum cleaner ...

Findings show that impaired autophagy leads to muscle degeneration, inflammation, and mitochondrial defects, while ...