本文推荐一款名为Fastq-dupaway的新型去重复工具，其针对二代测序（NGS）数据中PCR重复序列去除的算力瓶颈，提出基于外排序与序列比对的两种核心模式，在保证去重准确性的同时将内存占用控制在2–10 GB，且支持单端与双端数据。该工具在处理百GB级Hi-C、RNA ...

A FASTQ file is a text file that stores the sequence data from clusters that pass the flow cell's filter. Demultiplexing is the first phase in creating a FASTQ file if specimens were multiplexed.

Whole genome sequencing (WGS) has the capacity to greatly enhance genomic knowledge and understand mysteries of life by utilizing the most advanced genetic sequencing technologies. WGS can be used for ...

Analysis of Roche KAPA Target Enrichment kit experimental data obtained on an Illumina sequencing system is most frequently performed using a variety of publicly available, open-source analysis tools.

The Bioinformatics track combines research training opportunities in addition to advanced courses in the field of biostatistics, computational sciences, and applied mathematics. Students from all ...