本研究针对HIV相关隐球菌性脑膜炎(CM)患者颅内压(ICP)升高导致的临床预后不良问题,通过前瞻性队列分析593例乌干达成人患者数据,首次系统阐述了脑灌注压(CPP=MAP-ICP)与2周死亡率的关系。研究发现41%患者存在CPP70mmHg的低灌注状态,时间依赖性分析显示异常CPP使 ...
历史上,对严重脑外伤(TBI)患者的监测主要集中在颅内压(ICP)和脑灌注压(CPP),以防止继发性脑损伤。事实上,ICP(eICP)的升高与死亡率的增加有关,因此监测ICP被视为衡量护理质量和遵守各种指南的一个标准。ICP监测代表了由多学科团队合作管理的护理 ...
The National University of Singapore animal use and care committee approved all experimental procedures. Drugs were obtained from Sigma Chemical Co (m-CPP, naloxone ...
Future Neurology. 2013;8(2):205-224. Multimodal monitoring including ICP, MAP, CPP, partial pressure of cerebral tissue oxygen, cerebral lactate, pyruvate, glucose, glycerol and glutamate by ...
Objectives: The evidence to guide therapy in pediatric traumatic brain injury is lacking, including insight into the intracranial pressure/cerebral perfusion pressure thresholds in abusive head trauma ...