Embryonic stem cells (ESCs) were first isolated in 1981 from mouse blastocysts 1,2 and subsequently from human blastocysts 3,4. Mouse ESCs (mESCs) originate from the inner cell mass (ICM) of a ...

The derivation of mouse and human iPSCs from terminally differentiated somatic cells has opened up new avenues to address important fundamental questions in developmental biology 1,2,3. iPSC ...

Someone stole your invention and filed for a patent on it? Derivation proceedings in the Patent Office may be an answer. The Leahy-Smith America Invents Act (AIA) amended 35 U.S.C. § 135 to replace ...