There is variability in when and how cells divide during the development of embryos. While researchers traditionally believed this variability was an obstacle that needed to be regulated, the Hiiragi ...

New research sheds light on embryonic mitosis, thanks to a combination of novel imaging techniques, CRISPR/Cas9 genome editing technology, a modern protein-knockdown system, and medaka, or Japanese ...

Timelapse of a gene-edited medaka fish embryo undergoing mitosis. The mitotic spindle – the green strands in the middle of the cells – can be seen aligning and segregating duplicated chromosomes, ...

Sox9, a master regulator of cartilage formation, switches its target genes dynamically during embryonic limb development ...

Cell division is one of the most fundamental processes of life. From bacteria to blue whales, every living being on Earth relies on cell division for growth, reproduction, and species survival. Yet, ...

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Scientists are exploring ways to mimic the origins of human life without two fundamental components: sperm and egg. They are coaxing clusters of stem cells – programmable cells that can transform into ...

A zebrafish embryo during the first cell division cycle, with the structural protein actin labelled, which marks the cell boundary and ingressing furrow. The image shows a time course from dark orange ...

Magdalena (Magda) Zernicka-Goetz, today a developmental and stem cell biologist at the University of Cambridge and California Institute of Technology, recalled being an artistic child who enjoyed ...

Cellular aggregates derived from human stem cells in previous studies could not be considered genuinely accurate human embryo models, because they lacked nearly all the defining hallmarks of a ...