This study illustrates the spatiotemporal dynamics of neuron subtype changes within the entorhinal cortex–hippocampal circuit during Alzheimer’s disease progression. EC-stellate neurons progressively ...

Why do memories fade in Alzheimer's disease—and can they be restored? University of California, Irvine researchers have uncovered a key mechanism underlying memory loss, showing for the first time ...

A longstanding question in neuroscience is how mammalian brains (including ours) adapt to external environments, information, and experiences. In a paradigm-shifting study published in Nature, ...

Researchers have discovered the mechanistic steps underlying a new type of synaptic plasticity called behavioral timescale synaptic plasticity (BTSP). The study reveals how the entorhinal cortex (EC) ...

A longstanding question in neuroscience is how mammalian brains (including ours) adapt to external environments, information, and experiences. In a paradigm-shifting study published in Nature, ...

A longstanding question in neuroscience is how mammalian brains, including ours, adapt to external environments, information and experiences. In a study published in Nature, researchers at the Jan and ...

The human brain continues to be built after we are born for far longer than previously recognized, suggests research by Shawn Sorrells, assistant professor of neuroscience in the Kenneth P. Dietrich ...

Just as gravity explains how two distant objects can sway each other’s movement in space, synaptic connections may explain how amyloid plaques coax distant tau tangles to spread in the brain. This is ...

When the brain encodes and consolidates memories, it often connects related experiences that happened in different places and ...

A new Nature Neuroscience study reveals that the ventromedial prefrontal cortex regulates how the hippocampus links related memories, preventing false associations. Researchers used advanced imaging ...