Chemical engineers have devised a simpler process for incorporating hydrophobic drugs into tablets or other drug formulations, using nanoemulsions. With this method, it may be possible to make many ...

Formulation development serves as a vital bridge between a drug substance and a drug product that will remain stable and ...

General aspects of polynomial interpolation theory. Formulations in different basis, e.g. Lagrange, Newton etc. and their approximation and computational properties ...

Lipid nanoparticle formulation has increased over the past two decades. LNPs have proven to be effective nano-based delivery vehicles for cytotoxic chemotherapeutic drugs, nucleic acid therapies and ...

CAMBRIDGE, MA -- About 60 percent of drugs on the market have hydrophobic molecules as their active ingredients. These drugs, which are not soluble in water, can be difficult to formulate into tablets ...

Suzanne Jansen, MSc, PharmD, ICON, says early-phase clinical success depends on flexible, simple formulations that support wide dose ranges, matching placebos, and robust stability. Formulations are ...

From vaccines to personalized cancer therapies, scientists are studying the use of mRNA across many clinical applications. However, there are several factors that are unique to mRNA drug product ...

Patients with some cancers, autoimmune diseases, and metabolic disorders often endure time-consuming intravenous (IV) infusions to receive the best protein-based treatments available. Because these ...