Dynamic remodeling of the endomembrane system is a core biological process essential for maintaining cellular compartmentalization and homeostasis. Proteins enriched in intrinsically disordered ...

"Emerging Fusion Protein Technologies Drive Innovation in Targeted Therapies Across Autoimmune, Cancer, Metabolic, and Cardiovascular Diseases" Boston, Dec. 11, 2025 (GLOBE NEWSWIRE) -- According to ...

A study looking at the biophysical properties of an abnormal protein driving cancer cells is giving scientists new therapeutic clues for how to treat ependymoma, the third most common childhood brain ...

The immune system (T cell) attacks a human tumor cell. A newly developed molecule brings together two powerful immunotherapy strategies in one treatment. Researchers at the University of Basel and ...

Research originally authored by Kanvasri Jonnalgadda, Lam R. Markely, Scott Estes, Shashi Prajapati at High-Throughput Analytical Group (HTAG)-Cell Culture Development, Biogen IDEC, Cambridge, and MA ...

Domain structure of the unrearranged PML protein and P/R fusion proteins. Note the same RBCC domain (e.g., RING finger, B-box, and coiled-coil) in the N-terminus but different in the C-terminus.