Princeton scientists are peering into the smallest corners of matter using an exceptional collection of sophisticated microscopes — some so big they fill a room. These remarkable instruments have ...

Scientists in the US and Israel have demonstrated an atomic force microscope that can take images of periodic processes with a time resolution of microseconds. This is an order of magnitude faster ...

Pioneering microbiologist Antoni van Leeuwenhoek made the best microscopes of the pre-industrial era with methods that he kept secret. But the first full-3D scans of two of his instruments reveal that ...

Some of the most powerful microscopic techniques allow biochemists to analyze single molecules inside cells or in solution. A new 3-D-printed microscope can perform these single-molecule measurements ...

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Left: Images of fluorescent particles that are above, at and below (top to bottom) the vertical position of best focus of a microscope. Calibrating the effects of lens aberrations on the apparent ...