Chemical synthesis and peptide ligation techniques have revolutionised the field of protein engineering by enabling the precise construction of peptides and proteins with tailored modifications. These ...

Nature makes amide bonds—the key linkages that string together amino acids in a polypeptide—like a knitting whiz. The ribosome in Escherichia coli bacteria, for example, can make eight amide bonds in ...

Amide Technologies has raised $16.5 million in venture capital to help commercialize its peptide production process. The process was developed from 2011 to 2017 in the lab of the Massachusetts ...

Many biological functions are regulated by the switching on and off of mechanisms triggered by the matching of a keyhole ...

A team at ETH Zurich developed a new peptide-based organocatalyst that handles macrocycle formation from start to finish.

The PurePep ® Sonata ® is a mid-pilot scale peptide synthesizer that has been designed to provide more reliable and robust workflows. PurePep Sonata introduces real-time flow technology to streamline ...

Scientists at the Ecole Polytechnique Fédérale de Lausanne (EPFL) have addressed a long-standing challenge in the pharmaceutical industry, with the development of a two-step, one-pot method for ...

The breakthrough could simplify the production of complex proteins used in cancer immunotherapy and other advanced medicines ...

For decades, a substantial number of proteins, vital for treating various diseases, have remained elusive to oral drug therapy. Traditional small molecules often struggle to bind to proteins with flat ...