BioTechniques

De-CIPHER-ing transcriptomes and proteins together with new RNA-seq technology

Introducing a new RNA-seq platform for intracellular multimodal profiling that could transform cancer research and ...

Single-Cell Multiomics Enables High-Resolution Vector Copy Number Profiling in CAR-T Therapies

Mission Bio, the leader in single-cell multiomics, published research in Molecular Therapy Advances showing that their ...
GEN

A Breakthrough in High-Plex Spatial Proteomics

Spatial omics is transforming how researchers understand tissue biology, revealing the complex interplay between cells in health and disease. While RNA expression studies provide important molecular ...
ascopubs.org

HER2 Protein Overexpression, mRNA Expression, and DNA Amplification Across Solid Tumors: Comparison of Next-Generation Sequencing–Based Assays With Immunohistochemistry

Real-World Plasma Thymidine Kinase Activity in High-Risk and Metastatic Hormone Receptor–Positive, Human Epidermal Growth Factor Receptor 2–Negative Breast Cancer Treated With Cyclin-Dependent Kinase ...
The Manila Times

CAMP4 Therapeutics Preprints Pioneering Study on Regulatory RNA Profiling and Gene Upregulation

Capture-seq, CAMP4 has assembled what it believes to be the largest catalog of regRNAs ever compiled, uncovering thousands of previously undiscovered regRNAs in human cells ...
eLife

Evidence of off-target probe binding affecting 10x Genomics Xenium gene panels compromise accuracy of spatial transcriptomic profiling

Computational assessment identifies probe binding errors in a widely used commercial platform for spatial transcriptomics.
The Scientist

Using High-plex Protein Profiling to Discover Links Between Genes and Disease

Protein characterization can help scientists better understand how molecular events influence health and disease and identify causal factors for disease states. Researchers use human genome sequencing ...
GEN

Single-Cell Protein Profiling Solution

Scale Biosciences and Revvity’s BioLegend launched what they describe as a first-of-its-kind solution for high-parameter protein profiling of single cells. The TotalSeq™ Phenocyte™ single-cell protein ...