编者按：急性肾盂肾炎是常见的严重感染性疾病，可导致肾脏瘢痕化甚至肾功能丧失。然而，在耐药菌尤其是产超广谱β-内酰胺酶菌株高流行的背景下，临床面临两难困境：传统药物存在接种效应导致疗效不稳定，而碳青霉烯类虽疗效确切却易被过度使用。在2026年欧洲临床微 ...

Guidelines for the management of acute pyelonephritis in children currently recommend that oral antibiotic therapy is preceded by parenteral treatment with a third-generation cephalosporin. This ...

Montini G (2007) Antibiotic treatment for pyelonephritis in children: multicentre randomized controlled non-inferiority trial. BMJ 335: 386 Acute pyelonephritis is a serious disease, especially for ...

The urinary system is the drainage system of the human body for removing waste and extra water. It consists of the two kidneys, two ureters (which connect the kidneys and the bladder), a bladder and a ...

This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they ...

Urinary tract infections (UTIs) are a severe public health problem that are caused by a range of different pathogens. When the infection migrates to the upper urinary tract or is seeded there via ...

THE clinical diagnosis of pyelonephritis is frequently overlooked, and the disparity between the clinical and post-mortem findings in this infection has been emphasized repeatedly. 1–4 The failure of ...

It has been difficult to devise a practical clinical approach to reliably separate simple urinary tract infections (UTIs) from UTIs that also involve the kidneys (acute pyelonephritis). The gold ...

Acute pyelonephritis is a bacterial infection of the kidneys that affects up to 2 percent of pregnant women. In most cases, the infection first develops in the lower urinary tract. If it’s not ...

I often find myself under- or overestimating the incidence of certain nephrology-related conditions. I know this "error" is, in part, due to an "exposure bias" in my practice. I tend to overestimate ...

A kidney infection, or pyelonephritis, is a serious medical condition that occurs when harmful bacteria enter and infect the kidneys. The infection typically starts in the bladder or urinary tract and ...

Q: Which doctor should I consult for pyelonephritis? A: Consult an urologist, if you are getting recurrent UTI or pyelonephritis. If urologist is not available you should consult a nephrologist for ...