Observational analyses can complement randomized clinical trial findings for the study of HPV vaccine effectiveness

Led by researchers at NDORMS as part of the Data Analysis and Real World Interrogation Network (DARWIN EU) initiative, a new ...
ascopubs.org

Effect of an Invitation or the Effect of Participation: What Should Randomized Controlled Trials of Cancer Screening Examine?

Personalized Chemotherapy on the Basis of Tumor Marker Decline in Poor-Prognosis Germ-Cell Tumors: Updated Analysis of the GETUG-13 Phase III Trial Earlier detection of cancer offers an opportunity to ...
Applied Clinical Trials Online

How Sponsor Expectations Are Reshaping Data Strategy and Trial Design

In this video interview, Marc Buyse, ScD, founder and CEO of IDDI, reflects on the gap between sponsor expectations and statistical reality, drawing on lessons from the COVID era to argue for more ...
News Medical

Randomized clinical food trials: Best clinical practice, quality management & data processing

Thought LeadersAoife Hayes, Kevin O'Regan & Julie ScanlonClinical Trials Assitant, Operations Manager & Quality Assurance ManagerAtlantia Clinical Trials Food clinical trials may not be as familiar to ...
ascopubs.org

Pragmaticism in Cancer Clinical Trials

Results from the randomized trial indicated that no difference in clinical efficacy was seen between low- and high-dose folinic acid or the addition of levamisole versus placebo, which could help ...
Healthcare in Europe

Radiation for joint pain? Study validates low-dose approach for knee osteoarthritis

The concept of using radiotherapy for osteoarthritis may seem counterintuitive for many clinicians. Yet a well-designed ...
Edzard Ernst

The 1835 Nuremberg Salt Trial of Homeopathy: Background, Execution and Consequences

This landmark study, often called the "Nürnberger Kochsalzversuch", is historically significant as probably the first ...