A recent mouse model based study suggests that blocking TGF-β may improve osteoporosis treatment by helping quiescent ...

The liver's ability to communicate with other organs is crucial for maintaining homeostasis, particularly through signaling pathways. During liver regeneration, communication with organs such as the ...

Investigating the association of WNT pathway dysregulation and young-onset colorectal cancer. This is an ASCO Meeting Abstract from the 2024 ASCO Gastrointestinal Cancers Symposium. This abstract does ...

Suppression of the TGF-β/Smad pathway via a Smad7/Smurf2-dependent ubiquitination mechanism, and direct disruption of the apoptosis-resistant barrier in HSCs. This work extends the role of CTSK beyond ...

A recent mouse model based study suggests that blocking TGF-β may improve osteoporosis treatment by helping quiescent ...

“A fundamental hypothesis we sought to test was whether biomarkers from the TGF-β signaling pathway might be of novel value in risk stratification of HCC in the clinical cirrhotic setting.” ...

Liver fibrosis is characterized by the excessive deposition of extracellular matrix, a process primarily driven by activated hepatic stellate cells ...