Significance testing, with appropriate multiple testing correction, is currently the most convenient method for summarizing the evidence for association between a disease and a genetic variant.

Since Kimura (1968) and King & Jukes (1969) first suggested that most polymorphisms are selectively neutral, testing the neutral hypothesis has been one of the prime objectives of molecular population ...

MANOVA is a statistical test that extends the scope of the more commonly used ANOVA, that allows differences between three or more independent groups of explanatory (independent or predictor) ...